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Research Article

Catheter-based transendocardial gene delivery for therapeutic myocardial angiogenesis

Pages 67-70 | Published online: 10 Jul 2009
 

Abstract

it is unknown which is the most effective and safest delivery strategy for therapeutic myocardial angiogenesis. The enhancing effect of direct intramyocardial injection of angiogenic factors using either open-chest or catheter-based approaches on collateral function has been reported to occur in experimental models and among patients. This report reviews the rationale and current experience of using a catheter-based approach as a promising platform for proangiogenic intramyocardial gene delivery strategy. (Int J Cardiovasc Intervent 2000; 3: 67–70)

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