Abstract
The use of gamma‐hydroxybutyrate (GHB) in the UK has been mainly associated with the club scene in major cities. GHB dependence has previously been reported in the UK. We report on a case of GHB dependence presenting as lone use in a rural setting. A young male was admitted to hospital in Bangor, North Wales following an overdose of GHB. He was manufacturing GHB at home from readily available precursors. He was also using GHB in a dependent manner with ‘around the clock’ GHB dosing. GHB detoxification was undertaken in a medical setting but presented significant management problems. The patient rapidly became delirious with auditory and visual hallucinations, disorientation and severe agitation. We have reviewed the available literature on GHB dependence and withdrawal.