Cognitive function in amyotrophic lateral sclerosis

Abstract

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder of unknown etiology. Although there was a widely held belief that ALS does not cause cognitive impairment, cognitive function in patients with ALS has received more attention recently. In this paper, we discuss the clinical, neuroanatomical and neuropathological basis for cognitive dysfunction in ALS. (ALS 2000; 1: 343–347)

• Cognitive Function Amyotrophic Lateral Sclerosis Motor Neuron Disease Frontal Lobe Dysfunction Single Photon Emission Computerized Tomography Magnetic Resonance Spectroscopy Positron-EMISSION Computerized Tomography