Combined cell-gene therapy for lung cancer: rationale, challenges and prospects

Ricky M. ThakrarLungs for Living Research Centre, UCL Respiratory, University College London, Rayne Institute, London, UK;Department of Thoracic Medicine, University College London Hospital, London, UKCorrespondence[email protected]

Elizabeth K. SageLungs for Living Research Centre, UCL Respiratory, University College London, Rayne Institute, London, UK

Sam M. JanesLungs for Living Research Centre, UCL Respiratory, University College London, Rayne Institute, London, UK;Department of Thoracic Medicine, University College London Hospital, London, UK

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Declaration of interest

S Janes is a Wellcome Trust Senior Fellow in Clinical Science (WT091730MA) supported by the Roy Castle Lung Cancer Foundation, Rosetrees Trust, the Welton Trust, the Garfield Weston Trust and UCLH Charitable Foundation. The cell therapy for lung cancer trial is supported by MRC DPFS scheme MR/M015831/1. UCLH/UCL received a proportion of funding from the Department of Health’s NIHR Biomedical Research Centre’s funding scheme, the UCL ECMC, and the CRUK Lung Cancer Centre of Excellence. E Sage is a clinical lecturer funded from cell therapy for lung cancer trial, supported by MRC DPFS scheme. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

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Combined cell-gene therapy for lung cancer: rationale, challenges and prospects

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