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Declaration of interest
The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.
Reviewer disclosures
Peer reviewers on this manuscript have no relevant financial or other relationships to disclose
Additional information
Funding
The work of the authors is supported grants from U.S. Department of Health and Human Services, National Institutes of Health, National Institute of Neurological Disorders and Stroke (NS094615) and U.S. Department of Health and Human Services, National Institutes of Health (RO1 CA203493)