520
Views
15
CrossRef citations to date
0
Altmetric
Review

The comorbidity of epilepsy and depression: diagnosis and treatment

&
Pages 1321-1333 | Received 12 Jan 2016, Accepted 17 Jun 2016, Published online: 01 Jul 2016
 

ABSTRACT

Introduction: Depression can seriously affect the quality of life of epileptic patients and can even lead to suicide. Understanding the regularity, prevention and treatment of depression in patients with epilepsy (PWE) contributes to the improvement of their quality of life.

Areas covered: In this paper, we retrospectively analyzed the relevant literature on the pathogenesis, related factors, clinical characteristics, diagnosis and treatment of depression in PWE. A literature search utilized the PubMed, Embase and Google Scholar databases.

Expert commentary: PWE often have depression, which can be the result of seizures, antiepileptic drugs (AEDs) or social-demographic factors. It needs to be better understood, and the diagnosis should be more comprehensive for early treatment.

Declaration of interest

This work was supported by the National Natural Science Foundation of China (grant number 81271445, 81501122). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.