Declaration of interest
N Knuckey and B Meloni are named inventors on several patents for the use of CARPs as therapeutic agents. In addition, N Knuckey, B Meloni. and D Blacker. are shareholders in Argenica Therapeutics, which is a company developing R18 as a stroke therapeutic. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or conflict with the subject matter or materials discussed in this manuscript apart from those disclosed Citation10.
Reviewer disclosures
Peer reviewers on this manuscript have no relevant financial or other relationships to disclose Citation6.