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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 17, 2002 - Issue 6
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Research Article

A First Cyclopenta [c] thiophene Dimer as a New Bivalent Potent Cytotoxic Derivative

Lan Pham Khanh Centre d'Etudes et de Recherche sur le Médicament de Normandie, UFR des Sciences Pharmaceutiques, Université de Caen Basse-Normandie, 1, rue Vaubénard, 14032 Caen cedex, France
,
Patrick Dallemagne Centre d'Etudes et de Recherche sur le Médicament de Normandie, UFR des Sciences Pharmaceutiques, Université de Caen Basse-Normandie, 1, rue Vaubénard, 14032 Caen cedex, France
,
Henriette Landelle Centre d'Etudes et de Recherche sur le Médicament de Normandie, UFR des Sciences Pharmaceutiques, Université de Caen Basse-Normandie, 1, rue Vaubénard, 14032 Caen cedex, France
&
Sylvain Rault Centre d'Etudes et de Recherche sur le Médicament de Normandie, UFR des Sciences Pharmaceutiques, Université de Caen Basse-Normandie, 1, rue Vaubénard, 14032 Caen cedex, France
Pages 439-442 | Published online: 30 Sep 2008
 
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Abstract

Application of the bivalent approach to the cyclopenta [c] thiophene series led to a potent cytotoxic dimer.

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Related Research Data

Synthesis, Characterization, and Structure of Some 1,4-Disubstituted Cyclopenta[d][1,2]oxazines
Source: Wiley
The synthesis, characterization, and structure of a series of 4 -thieno[3,4- ]pyrroles and their corresponding pyrrolium cyanoborohydride salts
Source: (:unav)

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