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Original Article

Adverse reactions to dermal fillers: A review of European experiences

, MD, , , &
Pages 171-176 | Received 01 Jun 2005, Accepted 17 Aug 2005, Published online: 12 Jul 2009
 

Abstract

Background. In Europe, numerous dermal fillers have been utilized for the past decade. A lot of drawbacks have been reported and sometimes, severe complications occurred.

Objective. Our purpose is to report the clinical aspects of the adverse reactions following injections of some of the dermal fillers. Histological aspects of complications are also described.

Results. Adverse reactions secondary to biodegradable products are usually time limited, but with the non‐biodegradable products, we have observed severe, persistent, and recurrent complications. Histological examinations, in cases of non‐biodegradable products, may show the presence and persistence of the filler.

Conclusion. For the moment, there is no ideal dermal filler. All fillers can lead to adverse events and we need to inform patients fully before injecting. Clinical studies with long‐term follow‐up before launching a new product on the market are recommended. We believe that in Europe, at present, the CE mark is not a guarantee of safety of dermal fillers.

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