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ABSTRACT
Intense pulsed light (IPL) is a good option for erythema and telangiectasia of rosacea. Demodex, which is light and heat sensitive, is an important risk of Rosacea. Sometimes, IPL can induce rosacea aggravation. Here, we show two cases of erythema rosacea aggravated as pustule in several hours after IPL. Both cases show high density of Demodex after IPL. Neither of them had photosensitivity, systemic disease, or any other contraindication for IPL. One of the patients received IPL again after Demodex infection relieved and this time there was no inflammation induction. We need to attract more attention to IPL-induced rosacea aggravation and latent Demodex infection may act as a cofactor.
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Funding
This work was supported by Shanghai Pujiang Program [17PJ1408500], Talent youth program of Shanghai Health and Family planning system [2017YQ066] and Western medicine guidance project of Shanghai Science and Technology Commission [16411961700]. There is no any ethical/legal conflict involved in the manuscript.