Evaluation of the effect of autologous platelet-rich plasma on androgenic alopecia

ABSTRACT

In spite of several modalities for androgenic alopecia therapy used such as topical minoxidil solution or oral finasteride; it still has a great challenge. This study evaluated the effect of platelet-rich plasma in androgenic alopecia treatment regarding improvement percentage as well as the rate of adverse. Fifty patients complaining of androgenic alopecia were evaluated by Micro Viewer dermoscopy, analyzed by Compare view software and treated four times at one month interval with platelet-rich plasma injection. At every visit patient evaluation and satisfaction was completed, their age ranges from 18-40 years with a mean ± SD of 25.96 ± 5.99 years, the duration of hair loss ranges from 1-15 years with a mean ± SD of 4.58 ± 3.38 years. The mean Compare view software parameters showed a statistically significant increased from 261.47 ± 39.79 to 312.03 ± 48.61 for hair density, 0.64 ± 0.13 to 0.76 ± 0.16 for hair width and 2.25 ± 1.38 to 3.56 ± 2.71 for terminal/Vellus ratio (p < 0.05), additionally a high overall patient satisfaction in the absence of adverse effects. The present study indicates that APRP is a good tool for androgenic alopecia treatment in the absence of adverse effects.

KEYWORDS:

• Pattern
• hair
• alopecia
• androgenic

Acknowledgments

The authors acknowledge the Clinical Pathology Department, Faculty of Medicine, Al-Azhar University Assiut for preparation PRP.

Disclosure statement

The authors report no conflict of interest. No financial support was provided for the production of this study.