Concurrence of gestational diabetes and pre-gravid obesity (“diabesity”) in twin gestations

Teresinha SimõesDepartment of Maternal–Fetal Medicine Maternity Dr. Alfredo da Costa, Centro Hospitalar Lisboa Central and Universidade Nova de Lisboa, Lisbon, Portugal,

Alexandra QueirósDepartment of Maternal–Fetal Medicine Maternity Dr. Alfredo da Costa, Centro Hospitalar Lisboa Central and Universidade Nova de Lisboa, Lisbon, Portugal,

Sandra ValdoleirosDepartment of Maternal–Fetal Medicine Maternity Dr. Alfredo da Costa, Centro Hospitalar Lisboa Central and Universidade Nova de Lisboa, Lisbon, Portugal,

Ana Teresa MarujoDepartment of Maternal–Fetal Medicine Maternity Dr. Alfredo da Costa, Centro Hospitalar Lisboa Central and Universidade Nova de Lisboa, Lisbon, Portugal,

Nisa FelixDepartment of Maternal–Fetal Medicine Maternity Dr. Alfredo da Costa, Centro Hospitalar Lisboa Central and Universidade Nova de Lisboa, Lisbon, Portugal,

Isaac BlicksteinDepartment of Maternal–Fetal Medicine Maternity Dr. Alfredo da Costa, Centro Hospitalar Lisboa Central and Universidade Nova de Lisboa, Lisbon, Portugal, ;Department of Obstetrics and Gynecology, Kaplan Medical Center, Rehovot, Israel, and ;The Hadassah-Hebrew University School of Medicine, Jerusalem, IsraelCorrespondence[email protected]

Abstract

Objective: To assess the effect of the concurrence of gestational diabetes mellitus (GDM) and pre-gravid obesity in twin gestations (“diabesity”).

Methods: We compared perinatal outcomes of twin gestation in mothers with GDM and pre-gravid obesity (1.7%), mothers with GDM but with normal BMI (6.2%), and obese mothers without GDM (7.0%).

Results: Twin pregnancies with “diabesity” were associated with significantly higher incidence of stillbirth (OR = 6.4; 95%CI = 1.4, 33.4) and existing chronic hypertension (OR = 4.2; 95%CI = 1.2, 14.8) than in GDM pregnancies without obesity, and with births at 33–36 weeks as compared with the other groups. Otherwise, the comparisons showed remarkable similar results in terms of gestational age, birth weight, preeclampsia, cesarean section rate, and fetal-neonatal outcomes.

Conclusion: It appears that diabesity has a relatively minor effect in twins. If this will be confirmed by other studies, it would be important to elucidate how twins ameliorate the adverse outcomes of diabesity.

Keywords:

Declaration of interest

The authors report no conflict of interest.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Concurrence of gestational diabetes and pre-gravid obesity (“diabesity”) in twin gestations

Information for

Open access

Opportunities

Help and information

Concurrence of gestational diabetes and pre-gravid obesity (“diabesity”) in twin gestations

Abstract

Declaration of interest

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature