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Original Research

Demographic profile, clinical characteristics and medical management patterns of Indian coronary artery disease patients: a nationwide urban-based, real-world, retrospective, observational electronic medical record study– report of baseline data

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Pages 769-775 | Received 07 Apr 2021, Accepted 09 Jun 2021, Published online: 05 Jul 2021
 

ABSTRACT

Background: This is the first detailed Indian electronic medical record (EMR)-based real-world observational study to understand the clinical characteristics, associated comorbidities/risk factors and treatment(s) of CAD patients across India.Methods: EMR data of adult Indians (aged ≥ 18 years) diagnosed with CAD was retrospectively analyzed.Results: The majority of the participants had stable IHD (93%), were men (68.5% in ACS, 59.8% in stable IHD), most common age group was 40–64 years in ACS (56.6%) and stable IHD (51.4%). Both are common in metros (ACS 52%, 62% stable IHD). There is a high frequency of hypertension (38.2% in ACS, 59% in stable IHD) and diabetes mellitus (32.3% in ACS, 57.6% in stable IHD). Most common treatments are antiplatelet drugs and lipid-lowering drugs (96%).Conclusions: In India, stable IHD is the most prevalent form in vast majority of patients. The patients with CAD are mostly males, are mainly located in metros and majority fall between the age group of 40–64. The major comorbidities are hypertension and diabetes mellitus. Sociodemographic and clinical characteristics for CAD in India may not be similar to what is reported from the west. There is a significant difference in drug usage and adherence to guidelines in India for CAD.

KEYWORDS:

Abbreviations

EMR - Electronic Medical Records, CAD- Coronary Artery Disease, IHD- Ischemic Heart Disease, ACS-Acute Coronary Syndrome, BMI-Body Mass Index, BP-Blood Pressure, TIA-Transient Ischemic Attack.

Acknowledgments

The authors thank PharmaSolutions360 LLC for their support to the preparation of the manuscript.

Ethics approval

The study protocol was approved on 06/11/2020 by the Surakhsha- Ethics Committee, Asian Institute of Medical Sciences, Plot 72, Milap Nagar, MIDC, Dombivli, 421,203.

Availability of data and material

The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.

Author contributions

MY Khan, SA Pandit, K Gauray and A Mane developed the concept and performed the study. SS performed data analysis. YK and SP drafted the manuscript. A

ll authors reviewed the manuscript and gave final approval.

Declaration of interest

S Guha, U Jadhav and MS Rao are board members for Dr Reddy’s Laboratories Ltd. MY Khan, S Pandit, K Gaurav and A Mane are members of the Medical Affairs Department in Dr Reddy’s Laboratories Ltd. S Shah is an employee of Healthplix. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

Additional information

Funding

This paper was funded by Dr. Reddy’s Lab Ltd.