Diterpene derivative and chromone from Hypericum Perforatum

Abstract

A novel diterpene derivative, 5-methyl-5-(4,8,12-trimethyl-tridecyl)-dihydro-furan-2-one (1) and a new chromone, 5-hydroxy-7-methoxy-3-methyl-chromen-4-one (2), along with a known compound, phytol (3) have been isolated from the aerial parts of Hypericum perforatum. Their structures were established on the basis of spectroscopic analysis and by comparison with published values.

Keywords:

• Hypericum perforatum
• Guittiferae
• 5-Methyl-5-(4,8,12-trimethyl-tridecyl)-dihydro-furan-2-one
• 5-Hydroxy-7-methoxy-3-methyl-chromen-4-one
• Phytol

Acknowledgment

The authors wish to acknowledge financial support from Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People’s Republic of China.

Notes

^aRecorded in CDCl₃ at 400 MHz, J values in Hz; ^bRecorded in CDCl₃ at 100 MHz.

^aRecorded in CDCl₃ at 400 MHz, J values in Hz; ^bRecorded in CDCl₃ at 100 MHz.