p-O-Geranylcoumaric Acid from Melicope Lunu-Ankenda

Abstract

Leaf extracts of Melicope lunu-ankenda were chemically studied and found to contain mixtures of hydrocarbons and squalene, fatty acids and esters. A geranylated coumaric acid was isolated as the major compound. The crude dichloromethane and methanol extracts of the leaves were found to be strongly larvicidal with LC₅₀ values below 20 µg mL⁻¹. This is a first isolation of p-O-geranylcoumaric acid from this plant.

Keywords:

• p-O-Geranylcoumaric acid
• Melicope lunu-ankenda

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G.C.L. EE *

*Corresponding author