Longifoamide-A and B: Two new ceramides from Mentha longifolia (Lamiaceae)

Abstract

Two new N-acylsphingosines (ceramides) named longifoamide A {6′-tetracosenamide, (6′-Z)-N-[2,3-dihydroxy-1-(hydroxymethyl)octadecyl]} and B {6′-tetracosenamide, (6′-Z)-N-[2,3,4-trihydroxy-1-(hydroxymethyl)octadecyl]} were isolated from a methanol extract of Mentha longifolia. Both ceramides were characterized with the aid of 1D and 2DNMR spectroscopic techniques and high resolution mass spectrometry.

Keywords:

• Ceramides
• Longifoamides A and B
• Mentha longifolia
• Lamiaceae
• Characterization
• 1D and 2D NMR
• HRMS

Acknowledgements

We are thankful to Dr. Abdul Rasheed, Department of Botany, Peshawar University, for the identification of plant material.