A new bioactive triterpenoid saponin from the seeds of Lactuca scariola Linn.

Abstract

A new triterpenoid saponin, 3-O-[β-D-galactopyranosyl-(1 → 3)-O-β-D-xylopyranosyl-(1 → 4)-O-α-L-rhamnopyranosyl]-oleanolic acid; has been isolated from the seeds of Lactuca scariola. Its structure was determined by various spectral analysis and chemical degradations. This compound shows antimicrobial activity against various bacteria and fungi.

Keywords:

• Lactuca scariola
• Compositae
• Seed
• Triterpenoid saponin
• Antimicrobial activity

Acknowledgments

The authors are thankful to Professor J.T. Rao, Head, Department of Chemistry, Dr H.S. Gour University, Sagar (M.P.), for providing laboratory facilities, Head, R.S.I.C. CDRI Lucknow for spectral data and elemental analysis and Professor T.R. Sahu, Head, Department of Botany, Dr H.S. Gour University, Sagar (M.P.) for providing microbial facilities.