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Abstract
Two new oleanane-type triterpene glycosides designated as Termiarjunoside I and Termiarjunoside II were isolated from stem bark of Terminalia arjuna (Combretaceae) and characterized as olean-1α,3β,9α,22α-tetraol-12-en-28-oic acid-3β-D-glucopyranoside (1) and olean-3α,5α,25-triol-12-en-23,28-dioic acid-3α-D-glucopyranoside (2) based on chemical and spectral data evidences. Both compounds 1 and 2 potently suppressed the release of nitric oxide and superoxide from macrophages and also inhibited aggregation of platelets.
Acknowledgement
Council of Scientific and Industrial Research (CSIR) is acknowledged for providing the financial assistance to one of us (GK).