Laurane-derived sesquiterpenes from the marine red alga Laurencia tristicha (Rhodomelaceae)

Abstract

Two new stereoisomers of laurane-derived brominated sesquiterpenes, 4-bromolaur-11-en-1,10α-diol (1) and 4-bromolaur-11-en-1,10β-diol (2), one new natural product, laur-11-en-1,10α-diol (3), together with 11 known compounds (4–14) were isolated and identified from the organic extract of the marine red alga Laurencia tristicha. Their structures and relative stereochemistry were established by analysis of mass and NMR spectroscopic techniques.

Keywords:

• Laurencia tristicha
• Rhodomelaceae
• Sesquiterpene

Acknowledgements

This work was supported by the National Natural Science Foundation of China (No. 30530080), by National Marine 863 project (No. 2007AA09Z403), and by the Department of Science and Technology of Shandong Province (No. 2006GG2205023). B.-G.W. wishes to acknowledge the Bureau of Qingdao Municipal Science and Technology for partial financially support (06-2-2-12-JCH).