Two new alkamides from roots of Acmella decumbens

Abstract

From the roots of Acmella decumbens (Sm) R.K. Jansen three compounds belonging to the alkamide family were isolated: (2E, 4E)-N-hydroxiphenylethyl-2,4-decadien-9-inamide (1); (4E, 6E)-N-isobutyl-4,6-undecen-10-inamide; (2) and (2Z)-N-phenylethyl-2-nonane-6,8-diinamide (3). The structures were determined by means of IR, MS, ¹H NMR, ¹³C NMR, DEPT 135 and COSY. Compounds 1 and 2 are reported for the first time, while 3 was previously isolated from Spilanthes acmella L.

Keywords:

• Acmella decumbens
• alkamides
• acmelline
• decumbine

Acknowledgements

The authors are thankful to Prof. Dr Luis Ariza Espinar (Museo Botánico de Córdoba, Universidad Nacional de Córdoba) for the identification of the species. This study was supported by PICT 1728 N° 2398 and SeCyT (UNC) grants.