Two novel decanedienamide derivatives, JBIR-07 and -08, from Streptomyces versipellis 4083-SVS6

Jun-ya Ueda Biomedicinal Information Research Center (BIRC), Japan Biological Informatics Consortium (JBIC), 2-42 Aomi, Koto-ku, Tokyo 135-0064, Japan

Motoki Takagi Biomedicinal Information Research Center (BIRC), Japan Biological Informatics Consortium (JBIC), 2-42 Aomi, Koto-ku, Tokyo 135-0064, JapanCorrespondence[email protected]

Kazuo Shin-ya National Institute of Advanced Industrial Science and Technology (AIST), 2-42 Aomi, Koto-ku, Tokyo 135-0064, JapanCorrespondence[email protected]

Abstract

Two novel compounds, JBIR-07 (1) and -08 (2), were isolated from a large-scale culture of Streptomyces versipellis 4083-SVS6. These compounds were determined to be novel decanedienamide derivatives, (6E, 8Z)-3-hydroxy-8-(hydroxymethyl)-2,6-dimethyldeca-6,8-dienamide (1) and (6Z, 8E)-3-hydroxy-6-(hydroxymethyl)-2,8-dimethyldeca-6,8-dienamide (2), based on spectroscopic data.

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Acknowledgement

This work was supported by a grant from the New Energy and Industrial Technology Development Organization (NEDO) of Japan.

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Two novel decanedienamide derivatives, JBIR-07 and -08, from Streptomyces versipellis 4083-SVS6

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Two novel decanedienamide derivatives, JBIR-07 and -08, from Streptomyces versipellis 4083-SVS6

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