Abstract
A new jacaranone derivative, 2-(1,6-dihydroxy-4-oxocyclohex-2-enyl) acetic acid (1), has been isolated from the whole plants of Senecio scandens var. incisus, together with three known compounds: 2′-(p-hydroxyl-cinnamoyl)-6′-jacaranone-D-glucopyranoside (2), 2′-caffeoyl-6′-jacaranone-D-glucopyranoside (3) and kampferol-3-rhamnoside (4). Their structures were elucidated on the basis of spectroscopic data analyses and by comparison with the related known compounds. Cytotoxic activities of 1 against three human tumour cell lines have been evaluated by the MTT method.
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Acknowledgements
The authors are grateful for the financial support of the ‘985 Project’ of the MINZU University of China (CUN985-03-03), and the Project for young teachers in the MINZU University of China (CUN10A), together with the ‘Programme of Introducing Talents of Discipline to Universities’ (B08044) and the “Project for Scientific and Technical Achievements in Industrialization” of the Beijing Education Commission.