Abstract
Two novel triterpene glycosides, paphlagonoside A (1) and B (2), were characterised as 28-O-[β-D-glucopyranosyl(1 → 2)-α- L-arabinopyranosyl(1 → 4)-β-D-glucopyranosyl]-hederagenin (1) and 28-O-[β-D-xylopyranosyl(1 → 4)-α- L-rhamnopyranosyl(1 → 3)-β-D-xylopyranosyl (1 → 6)-β-D-glucopyranosyl(1 → 2)-β-D-glucopyranosyl]-hederagenin (2) from Cephalaria paphlagonica (Dipsacaceae). In addition to these, a common natural product (hederagenin) (3) was also isolated. The structures of all compounds were identified by spectroscopic and chemical methods. The antimicrobial and antioxidant activities of the plant extracts were examined by MIC and DPPH activity methods, respectively.
Acknowledgements
The authors are grateful to Prof. Dr H. Sümbül and Asst. Prof. R.S. Göktürk for collection and identification of the plant, and Prof. Dr N. Arda and Assoc. Prof. Dr Ü.K. Yavaşoğlu for discussing the antioxidant and antimicrobial activity results. We thank our Faculty for NMR spectra and the Biology Department of our Faculty for ESI-MS analysis, respectively. We are also thankful to TUBITAK (107T028) for financial support.