A new xanthone from Garcinia nitida

Abstract

A detailed chemical study on the stem bark of Garcinia nitida has led to the isolation of five xanthones. They are 1,6-dihydroxy-5-methoxy-6,6-dimethylpyrano[2′,3′:2,3]-xanthone (1), inophyllin B (2), osajaxanthone (3), 3-isomangostin (4) and rubraxanthone (5). The structures of these compounds were established using mainly 1-D and 2-D NMR spectroscopy (¹H, ¹³C, DEPT, COSY, HMBC and HMQC) while molecular masses were determined via MS techniques; 1 is a new compound.

Keywords:

• Garcinia nitida
• Guttiferae
• xanthones

Acknowledgements

The authors gratefully acknowledge financial support provided by the Malaysian Government Science Fund Program, Associate Professor Dr Jegak Uli for collection of plant samples and Ms. Shareena Safiai for recording NMR spectra.