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Natural Product Research
Formerly Natural Product Letters
Volume 26, 2012 - Issue 24
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Antioxidant activity of polyphenol and ultrasonic extracts from fruits of Crataegus pentagyna subsp. elburensis

Kh. Rabiei Pharmaceutical Research Center, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran
,
S. Bekhradnia Pharmaceutical Research Center, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran
,
S.M. Nabavi Department of Biology, College of Sciences, University of Mazandaran, Babolsar, Iran
,
S.F. Nabavi National Elites Foundation of Iran, Tehran, Iran
&
M.A. Ebrahimzadeh Pharmaceutical Research Center, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, IranCorrespondence[email protected]
Pages 2353-2357 | Received 09 Jul 2011, Accepted 02 Oct 2011, Published online: 19 Mar 2012
 
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Abstract

The effects of two extracting methods on the total phenolic and total flavonoid contents of Crataegus pentagyna subsp. elburensis Waldst. & Kit. ex Willd fruit extracts were investigated. Antioxidant activities of polyphenol (PP) fraction and ultrasonic (US) extraction were evaluated with four different in vitro antioxidant tests. IC50 for DPPH radical-scavenging activity was 32.2 ± 1.6 for PP fraction and 36.7 ± 1.5 µg mL−1 for US extract. Reducing powers of extracts increased with the increase of their concentrations. PP fraction exhibited high reducing power at 2–32 µg mL−1. Extracts exhibited good H2O2 radical scavenging and Fe2+ chelating ability. Their high phenolic and flavonoid contents could be responsible for their antioxidant activity and pharmacologic actions.

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