A new bromobenzyl methyl sulphoxide from marine red alga Symphyocladia latiuscula

Abstract

A new bromophenol, 2,3,6-tribromo-4,5-dihydroxybenzyl methyl sulphoxide, was isolated from the EtOH extract of the marine alga Symphyocladia latiuscula. Its structure was confirmed by spectroscopic methods (1D- and 2D-NMR, HR-ESI-MS). This new bromophenol showed moderate antifungal activity against Candida albicans with MIC value of 37.5 µg mL⁻¹.

Keywords:

• marine red alga
• Symphyocladia latiuscula
• bromophenol
• antifungal activity

Acknowledgements

This study was supported by the Fundamental Research Funds for the Central Universities, Research Fund for the Doctoral Program of Higher Education of China (200804911002), National Natural Science Foundation of China (30901849) and Science and Technology Planning Project of Zhejiang Province, China (2009C33004).