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Natural Product Research
Formerly Natural Product Letters
Volume 27, 2013 - Issue 9
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Short Communication

A new phenylpropanoid from Peperomia tetraphylla

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Pages 837-840 | Received 07 Nov 2011, Accepted 03 Jun 2012, Published online: 16 Jul 2012
 

Abstract

A new phenylpropanoid, (+)-methyl 3-acetoxy-3-(7-methoxy-1,3-benzodioxol-5-yl) propanoate (1), was obtained from the 95% EtOH extract of entire plant of Peperomia tetraphylla. The structure was elucidated based on the spectral analysis (IR, 1-D and 2-D NMR and HRESIMS). The absolute configuration of 1 was determined as (3R) by referring to analogous compound's optical rotation. Cytotoxicity assays showed that compound 1 had a moderate inhibitory activity against the A549 cell line, weak inhibitory activity against the Hela and the HepG2 cell lines.

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