Two new glycosides from Vitex negundo

Jie HuangDepartment of phytochemistry, China Pharmaceutical University, Nanjing, 210009, P.R. China;College of Pharmacy, Institute of Traditional Chinese Medicine & Natural Products, Jinan University, Guangzhou, 510632, P.R. China

Guo-Cai WangCollege of Pharmacy, Institute of Traditional Chinese Medicine & Natural Products, Jinan University, Guangzhou, 510632, P.R. China;Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou, 510632, P.R. China

Chun-Hua WangDepartment of phytochemistry, China Pharmaceutical University, Nanjing, 210009, P.R. China;College of Pharmacy, Institute of Traditional Chinese Medicine & Natural Products, Jinan University, Guangzhou, 510632, P.R. China

Xiao-Jun HuangCollege of Pharmacy, Institute of Traditional Chinese Medicine & Natural Products, Jinan University, Guangzhou, 510632, P.R. China;Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou, 510632, P.R. China

Wen-Cai YeDepartment of phytochemistry, China Pharmaceutical University, Nanjing, 210009, P.R. China;College of Pharmacy, Institute of Traditional Chinese Medicine & Natural Products, Jinan University, Guangzhou, 510632, P.R. China;Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou, 510632, P.R. ChinaCorrespondence[email protected]

Abstract

Two new glycosides, 2-methyl pyromeconic acid 3-O-β-d-glucopyranoside-6′-(O-4″-hydroxybenzoate) (1), 6′-O-p-hydroxybenzoyl-gardoside (2) and four known iridoid glycosides (3–6) were isolated from the whole plant of Vitex negundo. Their structures were elucidated on the basis of spectroscopic methods including HR-ESI-MS, 1D and 2D NMR.

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Acknowledgements

This work was supported by grants from the Programme for Changjiang Scholars and Innovative Research Team in University (IRT0965) and Research Team Programme of Natural Science Foundation of Guangdong Province (No. 8351063201000003).

Notes

^† These authors contributed equally to this work.

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Two new glycosides from Vitex negundo

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Two new glycosides from Vitex negundo

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