A new oleanane-type triterpenoidal saponin from Pulsatilla chinensis

Abstract

A new oleanane-type triterpenoidal saponin, 3-O-β-d-glucopyranosyl-hederagenin 23-O-α-d-ribofuranoside (1), was isolated from the roots of Pulsatilla chinensis, and its structure was established on the basis of the spectral data. Compounds 2, 7 and 8 showed moderate cytotoxic activity by 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazoliumbromide assay.

Keywords::

• Pulsatilla chinensis
• Ranunculaceae
• triterpenoidal saponins
• 3-O-β-d-glucopyranosyl-hederagenin 23-O-α-d-ribofuranoside
• cytotoxic activity

Acknowledgements

This paper was funded by National Sciences Foundation of China (No. 81273402), the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD), Jiangxi Advantage Technology Innovation Team Project (No. 2010DQB01700), the Natural Science Foundation of Jiangxi Province (No. 20114BAB215045), and the Natural Science Foundation of Jiangsu Province (No. BK2012620).