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Abstract
A new lignan named tadehaginosin, together with a known compound 3,4-dihydro-4-(4′-hydroxyphenyl)-5,7-dihydroxycoumarin, was isolated from the aerial part of Tadehagi triquetrum. The new structure was determined by various spectroscopic techniques (1H and 13C APT, HSQC, HMBC, 1H–1HCOSY, NOESY and HR-ESI-MS). The two isolates were evaluated for their hypoglycemic effects in vitro. Biological investigation showed that both of them possessed the capability to increase glucose consumption by HepG2 cells.
Funding
The financial assistance given by the Natural Sciences Foundation of China [grant number 81202994] is gratefully acknowledged.
Notes
1. These authors contributed equally to this work.