![Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days]({"type":"image" , "src" : "/sda/5925/TOC-Subject-Sample-2021-Bioscience.jpg"})
Abstract
A new cyclic tetrapeptide, cyclo-(l-leucyl-trans-4-hydroxy-l-prolyl-d-leucyl-trans-4-hydroxy-l-proline) (1), was isolated from the co-culture broth of two mangrove fungi Phomopsis sp. K38 and Alternaria sp. E33. The structure of 1 was determined by analysis of spectroscopic data and Marfey's analytic method. Primary bioassay demonstrated that compound 1 exhibited moderate to high inhibitory activity against four crop-threatening fungi including Gaeumannomyces graminis, Rhizoctonia cerealis, Helminthosporium sativum and Fusarium graminearum as compared with triadimefon.
Acknowledgements
This work was supported by the National Natural Science Foundation of China (21102049), the Natural Science Foundation of Guangdong Province (9451064201003751), the Science and Technology Project of Guangzhou City (11C12100771), the Key Academic Program of the 3rd Phase ‘211 Project’ of South China Agricultural University (2009B010100001) and the national scholarship fund of China for studying abroad (for Dr Chunyuan Li, No. 201208440268).