A new alkaloid glycoside from the rhizomes of Aristolochia fordiana

Abstract

A new alkaloid glycoside named fordianoside (1), together with three known compounds arabinothalictoside (2), 6-O-p-coumaroyl-β-fructofuranosyl-(2 → 1)-α-d-glucopyranoside (3) and 4-[formyl-5-(hydroxymethyl)-1H-pyrrol-1-yl] butanoic acid (4), was isolated from the rhizomes of Aristolochia fordiana. The structure of 1 was established as (1S)-1,2,3,4-tetrahydro-7-hydroxy-1-[(4-hydroxybenzyl) methyl]-2,2-dimethyl-8-O-isoquinolinyl β-d-glucopyranoside by using chemical and spectroscopic methods including HR-ESI-MS, 1D and 2D NMR.

Keywords::

• Aristolochiaceae
• Aristolochia fordiana
• alkaloid glycoside

Acknowledgements

This research work was financially supported by Program for Changjiang Scholars and Innovative Research Team in University (IRT1193) and A Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD).