Primula latifolia Lapeyr. and Primula vulgaris Hudson flavonoids

Abstract

Three flavonoids were isolated from the leaf MeOH extracts of Primula latifolia Lapeyr. and Primula vulgaris Hudson collected from Italian Alps: rutin (1) and kaempferol 3-neohesperidoside (2) from P. latifolia, and kaempferol 3-β-O-glucopyranosyl-(1 → 2) gentiobioside (3) from P. vulgaris. The structures were assigned on the basis of their ¹H and ¹³C NMR data, including those derived from 2D NMR, as well as on HPLC–MS results. This article is the first to report on P. vulgaris tissue flavonoids after Harborne's study in 1968 and the first work ever on these compounds from P. latifolia.

Keywords::

• Primula latifolia
• Primula vulgaris
• Primulaceae
• flavonoids
• kaempferol O-glycoside
• quercetin O-glycoside