Leptopyrine, new alkaloid from Leptopyrum fumarioides L. (Ranunculaceae)

Abstract

A new type of isoquinoline alkaloid leptopyrine was isolated from the aerial parts of Leptopyrum fumarioides L. (Ranunculaceae) of Mongolian origin. The known alkaloids protopine and thalifoline were isolated for the first time from this the species. All structures were established by physical and spectral analyses.

Keywords::

• Leptopyrum fumarioides
• alkaloids
• leptopyrine

Acknowledgements

The authors would like to thank Dr D. Antonova, Dr Y. Mitrev, Dr M. Rogozherov, Dr D. Pantaleeva and Ms M. Marinova from the Institute of Organic Chemistry with Centre of Phytochemistry for the spectral measurements.

Supplementary material

Supplementary material relating to this article is available online, alongside Table S1 and Figures S1–S12.