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Natural Product Research
Formerly Natural Product Letters
Volume 29, 2015 - Issue 19
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Articles

New flavonoid glycosides and other chemical constituents from Clerodendrum phlomidis leaves: isolation and characterisation

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Pages 1850-1856 | Received 18 Nov 2014, Accepted 14 Jan 2015, Published online: 12 Feb 2015
 

Abstract

Phytochemical investigation of the plant Clerodendrum phlomidis Linn. F. (Lamiaceae) has now led to the isolation of two new flavonoid glycosides (1, 2) together with six known compounds identified as pectolinaringenin (3), pectolinaringenin-7-O-β-d-glucopyranoside (4), 24β-ethylcholesta-5,22E,25-triene-3β-ol (5), 24β-ethylcholesta-5,22E,25-triene-3β-O-β-D-glucopyranoside (6), (2S,3S,4R,10E)-2-[(2′R)-2′-hydroxytetracosanoylamino]-10-octadecene-1,3,4-triol (7) and andrographolide (8) mainly by spectroscopic analysis. Compounds 4 and 68 are reported for the first time from C. phlomidis.

Acknowledgements

The authors express their gratitude to the Director, IICB, for laboratory facilities. This work received financial assistance from the Council of Scientific and Industrial Research (CSIR) Government of India. B.Y., A.H., S.S., S.S. and A.K.M. are recipients of Research Fellowships and N.B.M. of an Emeritus Scientist grant from CSIR, India. Thanks are due to Dr B. Achari (Ex-Emeritus Scientist, CSIR), Dr Sukdeb Banerjee (Ex-Senior Principal Scientist, CSIR) for helpful suggestions and Mr E. Padmanaban for NMR spectra.

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