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Natural Product Research
Formerly Natural Product Letters
Volume 30, 2016 - Issue 2
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Articles

A new isoflavanone from the trunk of Horsfieldia pandurifolia

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Pages 131-137 | Received 24 Jan 2015, Accepted 14 Apr 2015, Published online: 29 Jun 2015
 

Abstract

A new isoflavanone, 2,2′-epoxy-4′-methoxy-3,7-dihydroxyisoflavanone (1), and a new natural coumaranone, 2-hyroxy-2-(4′-methoxybenzyl)-6-methoxy-3-coumaranone (2), along with 26 known compounds, were first isolated from the trunk of Horsfieldia pandurifolia. Their structures were elucidated by the means of spectroscopic analysis. Compound 1 was assessed for its cytotoxicity against five human tumour lines (HL-60, SMMC-7721, A-549, MCF-7 and SW-480), and the result showed that it has no activity.

Additional information

Funding

The authors thank the [grant number 31460086] from Natural Science Foundation of China, and the grant [grant number 2009CC018] from Yunnan Province of China for basic research in social development.

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