A new triterpenoid glycoside from the leaves and stems of Duranta repens

Abstract

A new triterpenoid glycoside (1) was isolated from the methanol extract of the leaves and stems of Duranta repens L. (Verbenaceae) along with 14 known compounds consisting of eight triterpenoids, four iridoids, one phenylethanoid glycoside and one flavonoid. The chemical structure of 1 was determined to be bayogenin 3-O-[β-D-glucopyranoside]-28-O-[α-L-rhamnopyranosyl-(1→5)-O-β-D-apiofuranosyl-(1→4)-O-α-L-rhamnopyranosyl-(1→2)-O-α-L-arabinopyranosyl] ester, based on spectroscopic data. In addition, the inhibitory effects of the isolates on lipoxygenase activity were examined. Among them, acteoside and apigenin resulted in 94 ± 3.6% and 82 ± 4.7% inhibition, respectively, at 0.5 mM.

Keywords:

• Duranta repens
• Vabenaceae
• triterpenoid glycoside
• lipoxygenase inhibitory effect

Acknowledgments

We express our appreciation to Mr K. Takeda and Mr T. Iriguchi of Kumamoto University for their measurement of the MS and NMR spectra.

Disclosure statement

No potential conflict of interest was reported by the authors.