Novel skeleton sesquiterpenoids isolated from guava leaves

Abstract

A chemical investigation of the plant Psidium guajava L., collected in Guangdong province, afforded two novel skeleton sesquiterpenoids 1 and 2. Compound 2 also known as isocaryolan-9-one was a new natural product. The structure of the novel compound 1 was determined as guavacid A by various spectroscopic methods. A possible biosynthetic pathway for 1 and 2 was proposed.

Graphical abstract

Keywords:

• Psidium guajava L
• sesquiterpenoid
• guavacid A
• isocaryolan-9-one

Disclosure statement

No potential conflict of interest was reported by the authors.

Funding

This work was supported by the National Natural Science Foundation of China [grant number 31201321]; Education Department of Hunan Province [grant number B13084]. Wen Ouyang is supported by The China Scholarship Council.