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Natural Product Research
Formerly Natural Product Letters
Volume 30, 2016 - Issue 18
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Review

A review on biological sources, chemistry and pharmacological activities of pinostrobin

Neeraj K. PatelDepartment of Natural Products, National Institute of Pharmaceutical Education and Research (NIPER), Mohali, India
,
Gaurav JaiswalDepartment of Natural Products, National Institute of Pharmaceutical Education and Research (NIPER), Mohali, India
&
Kamlesh K. BhutaniDepartment of Natural Products, National Institute of Pharmaceutical Education and Research (NIPER), Mohali, IndiaCorrespondence[email protected]
Pages 2017-2027 | Received 11 May 2015, Accepted 14 Aug 2015, Published online: 13 Dec 2015
 
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Abstract

Pinostrobin, a dietary bioflavonoid discovered more than 6 decades ago in the heart-wood of pine (Pinus strobus), has depicted many pharmacological activities including anti-viral, anti-oxidant, anti-leukaemic, anti-inflammatory and anti-aromatase activities. It is an inhibitor of sodium channel and Ca2+ signalling pathways and also inhibits intestinal smooth muscle contractions. In spite of the fact that pinostrobin has an application as functional foods, till-to-date no comprehensive review on pinostrobin has been carried out. Hence, the present review deals with the biological sources, chemistry and pharmacological activities of pinostrobin.

Graphical abstract

Acknowledgements

NKP and GJ thanks the Director, NIPER, SAS Nagar, India, for providing the facilities for the present review study. NKP was DST-Inspire Fellow, India, for PhD, and GJ was a recipient of NIPER fellowship (2013–2015) for master programme during the course of present study.

Disclosure statement

No potential conflict of interest was reported by the authors.

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