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Natural Product Research
Formerly Natural Product Letters
Volume 31, 2017 - Issue 5
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Research Article

A new C20-diterpenoid alkaloid from Aconitum soongaricum var. pubescens

Lin ChenSchool of Life Science and Engineering, Southwest Jiaotong University, Chengdu, China;Key Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Material Science and Engineering, Southwest Jiaotong University, Chengdu, China;School of Chemistry and Chemical Engineering, China West Normal University, Nanchong, China
,
Lianhai ShanSchool of Life Science and Engineering, Southwest Jiaotong University, Chengdu, China
,
Wenliang XuSchool of Life Science and Engineering, Southwest Jiaotong University, Chengdu, China
,
Jifa ZhangSchool of Life Science and Engineering, Southwest Jiaotong University, Chengdu, China
,
Shuai HuangSchool of Life Science and Engineering, Southwest Jiaotong University, Chengdu, ChinaCorrespondence[email protected]
&
Xianli ZhouSchool of Life Science and Engineering, Southwest Jiaotong University, Chengdu, China;Key Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Material Science and Engineering, Southwest Jiaotong University, Chengdu, ChinaCorrespondence [email protected]
Pages 523-528 | Received 13 Jan 2016, Accepted 13 May 2016, Published online: 21 Jun 2016
 
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Abstract

A new denudatine-type C20-diterpenoid alkaloid, pubesine (1), along with seven known diterpenoid alkaloids, altaconitine (2), 14-benzoylaconine (3), spicatine A (4), 14-benzoylaconine-8-palmitate (5), 14-O-acetylsenbusine A (6), senbusine A (7) and 14-acetylneoline (8) were isolated from the whole plant of Aconitum soongaricum var. pubescens. Their structures were elucidated by means of extensive spectroscopic analyses (NMR and HR-ESI-MS) and comparison with data reported in the literature. All compounds were evaluated for their cytotoxicity against H460, MCF-7 and Hep G2 human cancer cell lines.

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Related Research Data

A new C20-diterpenoid alkaloid from Aconitum soongaricum var. pubescens
Source: Figshare
A new C20-diterpenoid alkaloid from Aconitum soongaricum var. pubescens
Source: Figshare

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