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Natural Product Research
Formerly Natural Product Letters
Volume 31, 2017 - Issue 12
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Research Articles

Tetracyclic indole alkaloids with antinematode activity from Uncaria rhynchophylla

, , , , , , , & show all
Pages 1403-1408 | Received 19 Jun 2016, Accepted 22 Oct 2016, Published online: 11 Nov 2016
 

Abstract

A new tetracyclic indole alkaloid, 17-O-methyl-3,4,5,6-tetradehydrogeissoschizine, together with seven known ones, were isolated from the aerial part of Uncaria rhynchophylla. Their structures were unambiguously elucidated by spectroscopic methods and comparing with the literature data. Among them, compounds 1, 3, 4 and 68 showed potent to moderate antinematode activities against Panagrellus redivevus at a concentration of 250 μg/mL.

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