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Natural Product Research
Formerly Natural Product Letters
Volume 31, 2017 - Issue 12
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Research Articles

Two new arylalkenyl α,β-unsaturated δ-lactones with cytotoxic activity from the leaves and twigs of Cryptocarya concinna

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Pages 1409-1413 | Received 20 Jun 2016, Accepted 15 Oct 2016, Published online: 10 Nov 2016
 

Abstract

Tow new arylalkenyl α,β-unsaturated δ-lactones named cryptoconcatones K (1) and L (2) were obtained from the leaves and twigs of Cryptocarya concinna. Their structures were established on the basis of spectroscopic data (MS, 1D and 2D NMR). Compounds 1 and 2 showed cytotoxic activities with IC50 values of 4.5 and 3.9 μM against Huh7 cancer cell line, respectively.

Acknowledgement

The authors thank Prof. Z.-L. Huang for collecting and identifying the plants.

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