Isolation and characterization of four novel β-Sitosteryl esters from Salvadora persica Linn.

Abstract

Salvadora persica is virtuous to have a variety of phytoconstituents responsible for many biological activities some of them identified particularly while some are still to be acknowledged. A number of steroidal, glycosidic, terpenoids, saponins and functional esters are reported till date. The present study deals with extraction, isolation, and characterisation of four novel steroidal esters by systematic cold extraction of S. persica. The extracted phytoconstituents were characterised by sophisticated spectral UV, IR, NMR and MS, techniques. The reported four new β-Sitosteryl esters SP-2, 3, 5 and 6 were extracted and reported for the first time.

Keywords:

• Salvadora persica
• root hydroalcoholic extract
• phytochemical screening
• β-Sitosteryl esters
• structure elucidation

Acknowledgement

The authors are thankful to the Instrumentation Section, Jamia Hamdard, New Delhi for recording the NMR spectra. Arbro Pharmaceuticals, New Delhi, for screenning IR spectra and SAIF, Central Drug Research Institute, Lucknow for scanning Mass spectra. One of the authors (M.K) is greatful to University Grants Commission, New Delhi, for awarding a Senior Research Fellowship.