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Natural Product Research
Formerly Natural Product Letters
Volume 32, 2018 - Issue 14
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Research Article

A new (propylphenyl)bibenzyl derivative from Dendrobium williamsonii

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Pages 1699-1705 | Received 29 Aug 2017, Accepted 08 Oct 2017, Published online: 02 Nov 2017
 

Abstract

A new (propylphenyl)bibenzyl derivative, dendrowillol A (1), along with 22 known compounds were isolated from the whole plants of Dendrobium williamsonii. Their structures were elucidated by means of extensive spectroscopic analysis. Cytotoxicity evaluation against five human tumour lines showed that all the compounds tested displayed very weak cytotoxicity when compared with the positive control taxol, but selective inhibitory effects on HL-60 for several compounds tested were observed, with IC50 values ranging from 4.48 to 11.04 μM.

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