Advanced search
Publication Cover
Natural Product Research
Formerly Natural Product Letters
Volume 33, 2019 - Issue 8
Submit an article Journal homepage
212
Views
5
CrossRef citations to date
0
Altmetric
Research Articles

Two pairs of phenolic enantiomers from the leaves of Eucommia ulmoides Oliver

Jian-Kun YanSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, P.R. China;Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, P.R. China;Key Laboratory of Pharmacology of Traditional Chinese Medicine Formulae, Ministry of Education, Tianjin, P.R. China
,
Xu-Liu ShiSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, P.R. China;Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, P.R. China;Key Laboratory of Pharmacology of Traditional Chinese Medicine Formulae, Ministry of Education, Tianjin, P.R. China
,
Paul Owusu DonkorSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, P.R. China;Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, P.R. China;Key Laboratory of Pharmacology of Traditional Chinese Medicine Formulae, Ministry of Education, Tianjin, P.R. China
,
Xiu-Mei GaoSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, P.R. China;Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, P.R. China;Key Laboratory of Pharmacology of Traditional Chinese Medicine Formulae, Ministry of Education, Tianjin, P.R. China
,
Li-Qin DingSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, P.R. China;Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, P.R. China;Key Laboratory of Pharmacology of Traditional Chinese Medicine Formulae, Ministry of Education, Tianjin, P.R. ChinaCorrespondence[email protected]
&
Feng QiuSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, P.R. China;Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, P.R. China;Key Laboratory of Pharmacology of Traditional Chinese Medicine Formulae, Ministry of Education, Tianjin, P.R. ChinaCorrespondence[email protected]
Pages 1162-1168 | Received 20 Jan 2018, Accepted 03 Apr 2018, Published online: 04 May 2018
 
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Abstract

Two pairs of new phenolic enantiomers, (+)-eucophenolic A (1a), (-)-eucophenolic B (1b), (-)-eucophenolic C (2a), (+)-eucophenolic D (2b) were isolated from the leaves of Eucommia ulmodies Oliver by chiral enantiomeric resolution. Their structures were elucidated based on extensive spectroscopic analysis. The absolute configurations of 1a/1b and 2a/2b were determined by empirical method and the calculated ECD and OR. All compounds were tested for Hep G2 tumour cell lines. However, no compounds showed potential cytotoxic activities against Hep G2 in vitro.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related Research Data

Two pairs of phenolic enantiomers from the leaves of Eucommia ulmoides Oliver
Source: Figshare
Two pairs of phenolic enantiomers from the leaves of Eucommia ulmoides Oliver
Source: Figshare

Linking provided by 

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.