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Natural Product Research
Formerly Natural Product Letters
Volume 33, 2019 - Issue 13
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Research Articles

A new pregnane steroid from cultures of Aspergillus versicolor

, , , , , , , & show all
Pages 1885-1890 | Received 24 Feb 2018, Accepted 15 May 2018, Published online: 04 Jun 2018
 

Abstract

A new pregnane steroid, named aspergillon A (1), together with two known compounds, (22E,24R)-ergosta-5,7,22-trien-3β-ol (2) and (22E, 24R)-ergosta-4,6,8(14),22-tetraen-3-one (3) were isolated from cultures of the tin mine tailings-associated fungus Aspergillus versicolor. The new structure and absolute configuration were determined with the help of extensive spectroscopic analyses and quantum chemical calculations of the electronic circular dichroism (ECD) spectra.

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