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Natural Product Research
Formerly Natural Product Letters
Volume 33, 2019 - Issue 14
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Research Articles

Emerixanthone E, a new xanthone derivative from deep sea fungus Emericella sp SCSIO 05240

Mangaladoss Fredimoses Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica, Chinese Academy of Sciences, South China Sea Institute of Oceanology , Guangzhou, China
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Xuefeng Zhou Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica, Chinese Academy of Sciences, South China Sea Institute of Oceanology , Guangzhou, ChinaORCID Iconhttps://orcid.org/0000-0001-9601-4869
ORCID Icon,
Wen Ai Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica, Chinese Academy of Sciences, South China Sea Institute of Oceanology , Guangzhou, China
,
Xinpeng Tian Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica, Chinese Academy of Sciences, South China Sea Institute of Oceanology , Guangzhou, China
,
Bin Yang Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica, Chinese Academy of Sciences, South China Sea Institute of Oceanology , Guangzhou, China
,
Xiuping Lin Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica, Chinese Academy of Sciences, South China Sea Institute of Oceanology , Guangzhou, China
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Juan Liu Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica, Chinese Academy of Sciences, South China Sea Institute of Oceanology , Guangzhou, China
&
Yonghong Liu Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica, Chinese Academy of Sciences, South China Sea Institute of Oceanology , Guangzhou, ChinaCorrespondence[email protected]
 show all
Pages 2088-2094 | Received 15 Nov 2017, Accepted 07 Jun 2018, Published online: 17 Jun 2018
 
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Abstract

The marine fungus Emericella sp was isolated from the deep sea sediments. The fungus was identified by its morphology and ITS region. A new emerixanthone E (1) together with four (2–5) known emodin derivatives were isolated from the metabolites of the fungus Emericella SCSIO05240. The structures were elucidated on the basis of NMR spectroscopic analysis and mass spectrometry. The biological properties of those compounds (1–5) were explored for antimicrobial, antifungal and antitumor activity.

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