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Natural Product Research
Formerly Natural Product Letters
Volume 33, 2019 - Issue 19
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Research Articles

A new furan derivative from an endophytic Aspergillus tubingensis of Decaisnea insignis (Griff.) Hook.f. & Thomson

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Pages 2777-2783 | Received 11 Jan 2018, Accepted 11 Jul 2018, Published online: 06 Nov 2018
 

Abstract

A new furan derivative named 3-(5-oxo-2,5-dihydrofuran-3-yl) propanoic acid (1) was isolated for the first time. Its structure was elucidated by UV, IR, NMR, HR-ESI-MS and the single-crystal X-ray diffraction spectroscopic data. Meanwhile, the antifungal and antibacterial activities of compound 1 was tested, it exhibited potent antifungal activity against Fusarium graminearum with MIC value of 16 µg/mL and medium antibacterial activity against Streptococcus lactis with MIC value of 32 µg/mL.

Graphical Abstract

Disclosure statement

No conflict of interest was reported by the authors.

Additional information

Funding

This work was financed by the Natural Science Basic Research Plan in Shaanxi Province of China [grant number 2014JZ003] and Science & Technology Co-ordination & Innovation Project of Shaanxi Province [grant number 2016KTTSNY03-04]. The Natural Science Basic Research Plan in Shaanxi Province of China,Science & Technology Co-ordination & Innovation Project of Shaanxi Province

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