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Natural Product Research
Formerly Natural Product Letters
Volume 34, 2020 - Issue 6
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Short Communications

Protective effect of Epicatechin on APAP-induced acute liver injury of mice through anti-inflammation and apoptosis inhibition

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Pages 855-858 | Received 17 Mar 2018, Accepted 15 Jul 2018, Published online: 03 Nov 2018
 

Abstract

Epicatechin (EC) is the most effective compound in Euonymus alatus (Thunb.)Sieb, and possesses a series of benefits, including anti-inflammatory, antioxidant, antiobesity and anticancer effects. In this study, we investigated the protective effects of EC in Acetaminophen(N-acetyl-p-aminophenol, APAP)-induced acute liver injury in C57BL/6J mice and explored the possible mechanisms involved in these effects.

Acknowledgements

The study was supported by the National Natural Science Foundation of China (Grant No. 81560675).

Disclosure statement

The authors report no conflicts of interest in this work.

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