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Natural Product Research
Formerly Natural Product Letters
Volume 33, 2019 - Issue 20
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Research Articles

A new dimeric alkylresorcinol from the stem barks of Swintonia floribunda (Anacardiaceae)

ORCID Icon, , , , , , , & show all
Pages 2883-2889 | Received 15 May 2018, Accepted 04 Aug 2018, Published online: 07 Oct 2018
 

Abstract

From an EtOAc-soluble fraction of the stem barks of Swintonia floribunda (Anacardiaceae), one new dimeric alkylresorcinol named integracin E (1), together with 4 known compounds (25) were isolated. Their chemical structures were elucidated based on the spectroscopic data interpretation. The absolute configuration of 1 was determined by the specific rotation analysis of its acid-catalyzed hydrolysis product. Compound 1 showed potent tyrosinase inhibitory activity with an IC50 value of 48.2 μM.

Graphical Abstract

Disclosure statement

No potential conflict of interest was reported by the authors.

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